Publications

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1. P. K. Singh, A. Kapoor, R. M. Lomash, K. Kumar, S. C. Kamerkar, T. J. Pucadyil and A. Mukhopadhyay (2018) Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes. J. Cell Biol. doi: 10.1083/jcb. 201802.   

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2. D. Maheshwari, R. Yadav, R. Rastogi, A. Jain, S. Tripathi, A. Mukhopadhyay and A. Arora (2018) Structural and Biophysical Characterization of Rab5a from Leishmania Donovani. Biophys. J. 115: 1217-1230.

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3. J. K. Verma, R. Rastogi and A. Mukhopadhyay (2017) Leishmania donovani resides in modified early endosomes by upregulating Rab5aexpression via the downregulation of miR-494. PLoS Pathog 13(6): e1006459.

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4. S. Parashar and A. Mukhopadhyay (2017) GTPase Sar1 regulates the trafficking and secretion of the virulence factor gp63 in Leishmania. J. Biol. Chem. 292: 12111–12125.

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5. S. K. Shanmugam, K. Kumar, P. K. Singh, R. Rastogi and A. Mukhopadhyay (2016) Single GDP dissociation Inhibitor Protein regulates endocytic and secretory pathways in Leishmania. Sci. Rep. 6: 37058.

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6. R. Rastogi, J. K. Verma, A. Kapoor, G. Langsley and A. Mukhopadhyay (2016) Rab5 isoforms Specifically Regulate Different Modes of Endocytosis in Leishmania. J. Biol. Chem. 291: 14732–14746.

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7. S. Bahl, S. Parashar, H. Malhotra, M. Raje and A. Mukhopadhyay (2015) Functional characterization of monomeric GTPase Rab1 in the secretory pathway of Leishmania. J. Biol. Chem. 290:29993–30005.

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8. C. N. Ezougou, F. Ben-Rached, D. K. Mos, J. Lin, S. Black, E. Knuepfer, J. L. Green, S. M. Khan, A. Mukhopadhyay, C. J. Janse, I. Coppens, H. Yera, A. A. Holder and G. Langsley (2014) Plasmodium falciparum Rab5B is an N-terminally myristoylated Rab GTPase that is targeted to the parasite's plasma and food vacuole membranes. Plos One 3:e87695.

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9. R. Guha, D. Gupta, R. Rastogi, R. Vikram, G. Krishnamurthy, S. Bimal, S. Roy and A. Mukhopadhyay (2013) Vaccination with Leishmania hemoglobin-receptor-encoding-DNA protects against visceral Leishmaniasis. Science Transl. Med. 5:202ra121.

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10. S. Agarwal, R. Rastogi, D. Gupta, N. Patel, M. Raje, and A. Mukhopadhyay (2013) Clathrin-mediated hemoglobin endocytosis is essential for survival of Leishmania. BBA. Mole. Cell Res. 1833: 1065-1077.

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11. R. Madan, R. Rastogi, S., Parashuraman and A. Mukhopadhyay (2012) Salmonella acquires lysosome associated membrane protein 1 (lamp1) on phagosomes from golgi via sipc mediated recruitment of host syntaxin6. J. Biol. Chem. 287:5574-5587.

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12. S. Parashuram, R. Madan and A. Mukhopadhyay (2010) NSF independent fusion of Salmonella-containing late phagosomes with early endosomes. FEBS Lett. 584:1251-1256.

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13. N. Patel, S. B. Singh, S. K. Basu and A. Mukhopadhyay (2008) Leishmania requires Rab7-mediated degradation of endocytosed hemoglobin for their growth. Proc. Natl. Acad. Sci. USA.105:3980-3985.

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14. R. Madan, G. Krishnamurthy and A. Mukhopadhyay (2008) SopE-mediated recruitment of host Rab5 on phagosomes inhibits Salmonella transport to lysosomes. In: Autophagosome and Phagosome; Edited by: V. Deretic © Humana Press, Totowa, NJ. Methods in Molecular Biology, 445: 417-437.

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15. M. Bhattacharya, N. Ojha, S. Solanki, C. K. Mukhopadhyay, R. Madan, N. Patel, G. Krishnamurthy, S. Kumar, S. K. Basu and A. Mukhopadhyay (2006) IL-6 and IL-12 specifically regulate the expression of Rab5 and Rab7 via distinct signaling pathways. EMBO J. 25: 2878-2888.

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16. S. Parashuraman and A. Mukhopadhyay (2005) Assay and functional properties of SopE in the recruitment of Rab5 on Salmonella-containing phagosomes. Methods in Enzymol. .403: 295-309.

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17. G. Krishnamurthy, R. Vikram, S. B. Singh, N. Patel, S. Agarwal, G. Mukhopadhyay, S. K. Basu, and A. Mukhopadhyay (2005). Hemoglobin receptor in Leishmania Is a hexokinase located in the flagellar pocket.  J. Biol. Chem. 280:5884-5891.

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18. S. B. Singh, R. Tandon, G. Krishnamurthy, R. Vikram, N. Sharma, S. K. Basu and A. Mukhopadhyay (2003) Rab5 mediated endosome-endosome fusion regulates hemoglobin endocytosis in Leishmania donovani. EMBO J. 22: 5712-5722.

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19. A. Mukhopadhyay and S.K. Basu. (2003) Intracellular delivery of drugs to macrophages. Adv. Biochem. Engin. Biotechnol. 84: 183-209.

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20. K Mukherjee, S Parashuraman, G Krishnamurthy, J Majumdar, A Yadav, R Kumar, SK Basu and A Mukhopadhyay (2002) Diverting intracellular trafficking of Salmonella to the lysosome through activation of the late endocytic Rab7 by intracellular delivery of muramyl dipeptide. J. Cell Sci. 115: 3693-3701.

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21. K. Mukherjee, S. Parashuraman, M. Raje and A. Mukhopadhyay (2001) SopE acts as an Rab5-specific nucleotide exchange factor and recruits non-prenylated Rab5 on Salmonella-containing phagosomes to promote fusion with early endosomes. J. Biol. Chem. 276: 23607-23615.

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22. K. Mukherjee,  S. Siddiqi, S. Hashim, M. Raje, S.K. Basu and A. Mukhopadhyay (2000) Live Salmonella recruits NSF on phagosomal membrane and promotes fusion with early endosomes. J. Cell Biol. 148: 741-753.

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23. S. Hashim, K. Mukherjee, M. Raje, S.K. Basu and A. Mukhopadhyay (2000) Live Salmonella modulate expression of rab proteins to persist in a specialised compartment and escape transport to lysosomes. J. Biol. Chem. 275: 16281-16288.

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24. S. Srividya, R.P. Roy, S. K. Basu and A. Mukhopadhyay (2000) Scavenger receptor mediated delivery of muramyl dipeptide activates antitumour efficacy of macrophages by enhanced secretion of tumour suppressive cytokines. J. Leukocyte Biol. 67: 683-690.

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25. S. Srividya, R. P. Roy, S. K. Basu and A. Mukhopadhyay (2000) Selective activation of antitumor activity of macrophages by delivery of muramyl dipeptide using novel polynucleotide based carrier recognised by scavenger receptors. Biochem. Biophys. Res. Com. 268: 772-777.

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26. S. Sengupta, J. Tripathi, R. Tandon, M. Raje, R. P. Roy, S. K. Basu and A. Mukhopadhyay (1999) Hemoglobin endocytosis in Leishmania is mediated through a 46 kD protein located in the flagelar pocket. J. Biol. Chem. 274: 2758-2765.

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27. V. Prasad, S. Hashim, A. Mukhopadhyay, S. K. Basu, R.P. Roy (1999) Oligonucleotide tethered to a short polyguanylic acid stretch are targeted to macrophages: enhanced antiviral activity of a vesicular stomatitis virus specific antisense oligonucleotide.  Antimicrob. Agents Chemother.  43: 2689-2696.

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28. M. Barbieri, S. Hoffenberg, R. Roberts, A. Mukhopadhyay, A. Pomrehn, B.F. Dickey and P.D. Stahl (1998) Evidence for a symmetrical requirement for Rab5-GTP in vitro endosome-endosome fusion. J. Biol. Chem. 273: 25850-25855.

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29. A. Mukhopadhyay, A. M. Barbieri, K. Funato, R. Roberts and P.D. Stahl (1997) Sequential action of Rab5 and Rab7 regulate endocytosis in the Xenopus oocyte.  J. Cell Biol.  136: 1227-1237.

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30. A. Mukhopadhyay, K. Funato and P.D.Stahl (1997) Rab7 regulates transport from early to late endocytic compartments in Xenopus oocytes. J. Biol. Chem. 272: 13055-13059.

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31. K. Funato, W. Beron, C.Z. Yang, A. Mukhopadhyay, and P. D. Stahl (1997) Reconstitution of phagosome-lysosome fusion in streptolysin-o- permeabilised cells.  J. Biol. Chem. 272: 16147-16151.

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32. A. M.  Barbieri, R. L. Roberts, A Mukhopadhyay and P. D. Stahl (1996) Rab5 regulates the dyanamics of early endosome fusion. Minireview.  Biocell 20: 331-338.

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33. A. Mukhopadhyay and P.D. Stahl (1995) Bee venom phospholipase A2 is recognised by the macrophage mannose receptor. Arch. Biochem. Biophys. 324: 78-84.

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34. A. Mukhopadhyay, B. Mukhopadhyay and S.K. Basu (1995) Circumvention of multidrug resistance in neoplastic cells through scavenger receptor mediated drug delivery. FEBS Lett. 376: 95-98.

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35. R. Abraham, N. Singh, A. Mukhopadhyay, S.K. Basu, V. Bal and S. Rath (1995) Modulation of immunogenicity and antigenicity of proteins by maleylation to target scavenger receptors on macrophages.  J. Immunol.  154: 1-8.

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36. S. Basu, B. Mukhopadhyay, S. K. Basu and A. Mukhopadhyay (1994) Enhanced intracellular delivery of doxorubicin by scavenger receptor mediated endocytosis for preferential killing of histiocytic lymphoma cells in culture. FEBS Lett. 324: 249-254.

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37. B. Mukhopadhyay, A. Mukhopadhyay, and S. K. Basu (1993) Enhancement of tumouricidal activity of daunomycin by receptor mediated delivery: in vivo studies. Biochem. Pharmacol. 46: 919-924

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38. A. Mukhopadhyay, B. Mukhopadhyay, R. K. Srivastava and S. K. Basu (1992) Scavenger receptor mediated delivery of daunomycin elicits selective toxicity towards neoplastic cells of macrophage lineage. Biochem. J. 284: 237-241.

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39. A. Mukhopadhyay and S.K. Basu (1990) Enhanced intracellular delivery of methotrexate by a receptor mediated process. Biotech. Appl.  Bochem. 12: 529-536.

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40. G. Chaudhuri, A. Mukhopadhyay and S. K. Basu (1989) Selective delivery of drugs to macrophages through a highly specific receptor : An efficient chemotherapeutic approach against Leishmaniasis. Biochem. Pharmacol. 38: 2995-3002.

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41. A. Mukhopadhyay, G. Chaudhuri, S.K. Arora, S. Sehgal and S.K. Basu (1989) Receptor-mediated drug delivery to macrophages in chemotherapy of leishmaniasis. Science. 244: 705-707.